Yl Jiang,YANG Fengyuan,HUANG Xi,YAN Wenjie

( Department of Dermatology, Affiliated Hospital of Guilin Medical University, Guilin 541001, China)

Abstract Objective To evaluate the clinical efects and safety of percutaneous introduction of compound ammoniumglycyrrhizin solution in the treatment of erythema telangiectasia aene rosacea. ethods 75 patients with erythematelangiectasia rose acne were randomly divided into 3 groups. Group A ( 27 cases ) were treated with compoundammonium glyeyrrhizin solution combined with external medical cold dressing. Group B( 25 cases ) were treated withoral compound ammonium glyeyrthizin tablets combined with external medical cold dressing, and the control group23 cases) were treated with exteral medical cold dressing only. The treatment cycle of the 3 groups was 4 weeks.Results After treatment , the elicacy of the 3 groups was compared, and the difference was statistically significant( P<0.05 ). During the trial, 2 cases in Group A were experieneed transient worsening of symptoms and were subjected to dropout testing.Throughout the treatment process of the three groups of patients, no serous adverse reactionsoccurred. During the one month follow-up after treatment, there was no statistically significant diference inrecurrence rates among the three groups( P>0.05 ). Conclusion Percutaneous introduction of compound ammoniumglycyrrhizin solution in the treatment of erythema telangiectasia rose acne is clinically safe and effective.

Keywords : percutaneous introduction; compound ammonium glycyrrhizin; acne rosacea

DOI:10.19296/i.cnki.1008-2409.2024-04-009

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