LIANG Xue ^1② , YE Guishan ² , TAN Jie ¹ , HAN Minghui ¹ , XIA Chunbo ¹ , LI Zhongyuan ^1③

(1. Guangxi Key Laboratory of Brain and Cognitive Neuroscience, Guilin Medical University, Guilin 541199; 2. Dept. of Hospital-Acquired Infection Control, the Affiliated Hospital of Guilin Medical University, Guilin 541001, China)

Abstract Objective: To investigate the infection status of T. gondii in critical patients in the area of Guilin, Guangxi. Methods: 260 fasting venous blood samples of critical patients admitted in the Affiliated Hospital of Guilin Medical University from Nov. 2018 to Nov. 2019 were collected, then the serum was separated, and the serum IgG antibody level of T. gondii was detected by ELISA method. The correlation between T. gondii infection and gender, age and type of disease was analyzed, and all T. gondii IgG positive samples were identified through DNA extraction. Results: Our data showed that there were 73 male and 24 female critical patients with T. gondii IgG antibodies can be positive infection, with the seroprevalence rate of 37.31 % ; the seroprevalence rate in male was 41. 01 % , which is higher than 29.27 % in female; and there was no correlation between T. gondii infection and gender, age and disease type of critical patients (P>0.05) and no T. gondii-specific DNA sequences were detected in the serum samples of patients with positive IgG. Conclusion: The infection rate of T. gondii is higher in critical patients in Guilin region, but the age and type of disease are not the risk factors for the infection.

Keywords:Toxoplasma gondii; critical patient; Guilin region; DNA identification

DOI:10.19296/ j.cnki.1008-2409.2023-01-005

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