新生儿病理性黄疸的相关危险因素分析

方亚男,张艳星,袁巧云

(许昌龙耀医院儿科,河南 许昌 461700)

摘要 目的:采用 Logistic 回归方程分析新生儿病理性黄疸的影响因素。 方法:选取 355 例新生儿,统计病理性黄疸发生情况,收集临床资料,分析新生儿病理性黄疸的危险因素。 结果:355 例新生儿中,发生病理性黄疸的新生儿为 81 例,未发生的新生儿为 274 例,新生儿病理性黄疸发生率为22.82%;不同早产情况、合并 ABO 溶血、宫内感染、缺氧缺血性脑病、Apgar 评分、白蛋白水平的新生儿病理性黄疸发生率差异有统计学意义(P<0.05);早产、合并 ABO 溶血、宫内感染、缺氧缺血性脑病、Apgar 评分<7 分、白蛋白水平<25 g/ L 均为新生儿病理性黄疸的独立危险因素(P<0.05)。 结论:新生儿病理性黄疸危险因素较多,临床应针对其危险因素采取综合性措施进行积极干预,预防新生儿病理性黄疸发生。

关键词: 新生儿;病理性黄疸;影响因素

中图分类号:R722.17　　　　文献标志码:A　　　　文章编号:1008-2409(2022)03-0052-05

Related risk factors of neonatal pathological jaundice

FANG Yanan, ZHANG Yanxing, YUAN Qiaoyun. ( Dept. of Pediatrics, Xuchang Longyao Hospital, Xuchang 461700, China)

Abstract　 Objective: To analyze the influencing factors of neonatal pathological jaundice by logistic regression equation. Methods: A total of 355 neonates were selected, and the incidence of pathological jaundice was counted and the clinical data of the patients were collected so as to analyze the risk factors of neonatal pathological jaundice. Results: Among the 355 neonates, 81 neonates developed pathological jaundice, while 274 neonates did not, and the incidence of neonatal pathological jaundice was 22.82%. The incidence of pathological jaundice in neonates with different preterm conditions, complicated with ABO hemolytic, intrauterine infection, hypoxic-ischemic encephalopathy, Apgar scores, and albumin level showed statistical significances(P<0.05). Neonates with preterm conditions, complicated with ABO hemolytic, intrauterine infection, hypoxic-ischemic encephalopathy, Apgar score less than 7, and albumin level less than 25 g/ L are all considered as the independent risk factors for neonatal pathological jaundice (P<0.05). Conclusion: There are many risk factors for neonatal pathological jaundice, so comprehensive measures should be taken to prevent the occurrence of neonatal pathological jaundice.

Keywords: neonates; pathological jaundice; influencing factors

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